我们应用CAP方案大剂量冲击治疗19名肺癌患者,其中鳞癌11例,腺癌6例,小细胞未分化癌2例,治疗同时应用水化及甘露醇静脉点滴。同步观察血药浓度及细胞类型的关系,血药浓度与近期疗效的关系及血药浓度与肾功能关系。前两者经统计学处理无显著差异。治疗后有肾功能变化的6例。 We used the CAP regimen to treat 19 lung cancer patients with large doses of shocks, including 11 cases of squamous cell carcinoma, 6 cases of adenocarcinoma, and 2 cases of small cell undifferentiated carcinoma. The treatment was simultaneously applied hydration and mannitol intravenous drip. Simultaneously observe the relationship between blood drug concentration and cell type, the relationship between blood drug concentration and short-term efficacy, and the relationship between blood drug concentration and renal function. The first two were statistically processed without significant differences. There were 6 cases of changes in renal function after treatment.