To explore the diagnosis and operat ive treatment of radiation induced brachial plexopathy. Methods: Nine cases of radiation induced brachial plexopathy w ere divided into two groups, 4 cases undergoing neurolysis of brachial plexus as Group A and 5 cases undergoing transfer of myocutaneous flaps after neurolysis as Group B. In Group B, 4 cases were treated with latissimus dorsi myocutaneous flaps (about 20 cm×20 cm) and 1 case with pectoralis major myocutaneous flap (a bout 8 cm×6 cm). Results: All the 9 cases of radiation induced brachial plexopa thy were followed up for a period of 2 to 5 years, with an average of 2.3 ye ars. As far as pain relief and function recovery were concerned, the results of Group B were better than those of Group A. Conclusions: Based on the results of Group B in the series, we suggest that the procedure of covering the wounds with transferred myocutaneous flaps after neurolysis of the brachial plexus should be performed to those advan ced patients. The procedure may improve the blood supply of the fibrotic brachia l plexus by reestablishing a good nerve bed. To explore the diagnosis and operat ive treatment of radiation induced brachial plexopathy. Methods: Nine cases of radiation induced brachial plexopathy w ere divided into two groups, 4 cases undergoing neurolysis of brachial plexus as Group A and 5 cases undergoing transfer of myocutaneous flaps after neurolysis as Group B. In Group B, 4 cases were treated with latissimus dorsi myocutaneous flaps (about 20 cm × 20 cm) and 1 case with pectoralis major myocutaneous flap (a bout 8 cm × 6 cm). Results: All the 9 cases of radiation induced brachial plexoid thy was followed up for a period of 2 to 5 years, with an average of 2.3 ye ars. As far as pain relief and function recovery were concerned, the results of Group B were better than those of Group A. Conclusions : Based on the results of Group B in the series, we suggest that the procedure of covering the wounds with transferred myocutaneous flaps after neurolysis of the brachial plexus should be performed to those adva n ced patients. The procedure may improve the blood supply of the fibrotic brachia l plexus by reestablishing a good nerve bed.