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在西班牙加那利群岛有10种金丝桃属植物。作者研究了其中的 Hypericum ca-nariense L.、H.glandulosum Ait.、H.re-flexum L fil.和 H.grandifolium Chiosy的甲醇提取物对小鼠中枢神经系统(CNS)的影响,以及对抑郁症动物模型的作用。小鼠分别口服这4种植物的甲醇提取物500和1000mg/kg。结果显示,除了 H.re-flexum 提取物在2种剂量时显著增加(约47%)戊巴比妥诱导的睡眠时间外,其余3种植物提取物均无此作用。4种植物的提取物
There are 10 species of Hypericum in the Canary Islands of Spain. The authors studied the effects of methanol extracts of Hypericum ca-nariense L., H.glandulosum Ait., H.re-flexum L fil., and H. grandifolium Chiosy on the central nervous system (CNS) in mice, and on depression. The role of animal models. The mice were orally administered methanol extracts 500 and 1000 mg/kg, respectively. The results showed that except for the significant increase (about 47%) of the pentobarbital-induced sleep time in the two doses of H. re-flexum extract, the other three plant extracts did not. Four plant extracts