自从人类染色体不分离由Bridgs在1916年鉴定以来,提出了许多因素来说明其起因,但在人类中其遗传作用仍被一些人怀疑,反对。为了研究这个问题,作者估价了在高度近亲繁殖群体中Down综合征的资料。Kuwait是世界上近亲婚配率最高的地方之一,约有50%人近亲婚配。这份材料报告了在这些人中Down综合征发生率,及婴 Since the identification of human chromosomes by Bridgs in 1916, many factors have been proposed to explain their causes, but their genetic effects are still being questioned and opposed by some people in humans. To study this problem, the authors assessed Down syndrome in highly inbred populations. Kuwait is one of the highest rates of near-relatives in the world, with about 50% of close relatives married. This material reports the incidence of Down syndrome in these people, and infants