在人的肝癌发生过程中,何种细胞是恶性前期细胞,尚不清楚。Anthony 等将肝细胞的一种可能的恶性前期病变称为肝细胞增生异常dysplasia,其特征是肝细胞增大,核多形性伴染色质增多及多核。本文作者用显微测量方法,研究了400例正常、慢性活动性肝炎、肝硬变和肝细胞癌的活检或尸检标本,将增生异常的肝细胞分为两型,即大增生异常细 In the process of human liver cancer, what kind of cells are malignant pre-cells, it is not clear. Anthony et al. Refer to a possible premalignant lesion of hepatocytes as dysplasia, which is characterized by an increase in hepatocytes, an increase in nuclear pleomorphism with chromatin and multinuclear. The authors used microscopic measurements to study biopsy or autopsy specimens of 400 patients with normal, chronic active hepatitis, cirrhosis and hepatocellular carcinoma. The abnormally proliferating hepatocytes were divided into two types, namely hyperplasia