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An efficient synthesis ofα-D-GlcpNAc-(1→2)-[α-D-ManpNAc-(1→3)-]α-L-Rhap-(1→2)-α-L-Rhap-(1→3)-α-L-Rhap(1), the repeating unit of the O10 antigen from Acinetobacter baumannii was achieved via sequential assembly of the building blocks,p- methoxylphenyl 2,4-di-O-benzoyl-α-L-rhamnopyranoside(2);2-O-allyloxycarbonyl-3,4-di-O-bcnzoyl-α-L-rhamnopyranosyl tri- chloroacetimidate(3);4-methoxylphenyl 3-O-allyloxycarbonyl-4-O-benzoyl-α-L-rhanmopyranoside(4);2-azido-3-O-benzoyl-2- deoxy-4,6-O-isopropylidene-α-D-mannopyranosyl trichloroacetirnidatc(5);2-azido-3,4,6-tri-O-benzoyl-2-deoxy-α,β-D-glucopyr- ano syl trichloroacetimidatc(6).The total yield of 1 from 4 was 4.7%.
An efficient synthesis of α-D-GlcpNAc- (1 → 2) - [α-D-ManpNAc- (1 → 3)] α-L-Rhap- 3) -α-L-Rhap (1), the repeating unit of the O10 antigen from Acinetobacter baumannii was achieved via sequential assembly of the building blocks, p-methoxylphenyl 2,4-di-O-benzoyl-α-L-rhamnopyranoside 2-O-allyloxycarbonyl-3,4-di-O-bcnzoyl-α-L-rhamnopyranosyl tri-chloroacetimidate (3); 4-methoxylphenyl 3-O-allyloxycarbonyl-4-O-benzoyl-α-L 2-azido-3-O-benzoyl-2-deoxy-4,6-O-isopropylidene-α-D-mannopyranosyl trichloroacetirnidatc (5); 2-azido-3,4,6-tri- O-benzoyl-2-deoxy-α, β-D-glucopyran-ano syl trichloroacetimidatc (6) .The total yield of 1 from 4 was 4.7%.