抑癌基因（tumorsuppressgene）是正常细胞在调控细胞增殖、分化等方面起重要作用的基因。它的缺失或失活可引起细胞内癌基因（oncogene）的活化，造成细胞的过度增生、分化，导致恶性肿瘤的发生和发展。对癌基因和抑癌基因的研究是揭示致癌机理、发展新的基因疗法和制备新的抗 Tumor suppress gene (gene) plays an important role in regulating cell proliferation and differentiation. Its absence or inactivation can cause the activation of intracellular oncogenes, resulting in excessive proliferation and differentiation of cells, leading to the occurrence and development of malignant tumors. Research on oncogenes and tumor suppressor genes reveals carcinogenic mechanisms, development of new gene therapies, and preparation of new antibodies