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目的探讨轮状病毒肠炎合并高钠血症的临床特征及治疗效果。方法对2004年10月-2007年12月收住ICU并确诊为轮状病毒肠炎的126例患儿的临床资料进行回顾性分析。按高钠血症标准,根据入ICU后当天的血钠值将患儿分为高钠血症组及非高钠血症组。结果高钠血症组11例病死率为36.4%,非高钠血症组115例病死率为3.5%,两组死亡率相比有显著性差异(P<0.01)。高钠血症组中>160mmol/L死亡率为100%,<160mmol/L死亡率为22.2%,显示血钠值越高,死亡率越高。结论轮状病毒肠炎合并电解质紊乱常见,但合并高钠血症状比较少见,预示着患儿病情危急,预后差,且治疗时应注意补液张力和速度。
Objective To investigate the clinical features and therapeutic effects of rotavirus enteritis combined with hypernatremia. Methods The clinical data of 126 children admitted to ICU from October 2004 to December 2007 who were diagnosed as rotavirus enteritis were retrospectively analyzed. According to the criteria of hypernatremia, children were divided into hypernatremia group and non-hypernatremia group according to the blood sodium value after ICU. Results The mortality of 11 cases was 36.4% in hypernatremia group and 115% in non-hypernatremia group, with a significant difference (P <0.01). Hypernatremia group> 160mmol / L mortality was 100%, <160mmol / L mortality was 22.2%, showing that the higher the blood sodium value, the higher the mortality rate. Conclusions Rotavirus enteritis complicated with electrolyte imbalance is common, but the symptoms of combined hypernatremia are rare, which indicates the critical condition and the poor prognosis of children, and should pay attention to the tension and speed of rehydration.