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目的探讨经尿道电切术同期治疗膀胱尿路上皮细胞癌合并前列腺增生患者的临床疗效。方法选取2012年8月至2014年8月广州市中西医结合医院收治的57例膀胱尿路上皮细胞癌合并前列腺增生患者作为研究对象,按随机数字表法将其分为A组(27例)和B组(30例)。A组患者单纯行经尿道膀胱肿瘤电切术(TURBT),B组患者在A组基础上再行TURP,比较两组患者的肿瘤复发、膀胱颈部种植转移情况及B组患者手术前后残余尿量(RUV)、最大尿流率(Qmax)、生活质量指数(QOL)、国际前列腺症状评分(IPSS)。结果术后,B组患者RUV、QOL及IPSS均明显低于手术前,Qmax明显高于手术前,差异均有统计学意义(均P<0.05)。结论同期行TURBT和TURP对膀胱尿路上皮细胞癌合并前列腺增生患者进行治疗,疗效显著,安全性高,不会增加肿瘤复发及种植转移风险,且可有效解除尿路梗阻。
Objective To investigate the clinical efficacy of transurethral resection of the prostate in the treatment of bladder urothelial carcinoma with benign prostatic hyperplasia. Methods 57 cases of bladder urothelial carcinoma with benign prostatic hyperplasia admitted from Guangzhou Traditional Chinese and Western Integrative Hospital between August 2012 and August 2014 were selected as research objects and divided into group A (n = 27) according to random number table method And group B (30 cases). A group of patients with simple transurethral resection of the bladder tumor (TURBT), B group of patients in the A group based on TURP again, compared the two groups of patients with tumor recurrence, bladder neck metastasis and metastasis and residual volume of patients before and after surgery B group RUV, Qmax, QOL, IPSS. Results After operation, the RUV, QOL and IPSS in group B were significantly lower than those before operation. The Qmax in group B was significantly higher than that before operation (all P <0.05). Conclusions TURBT and TURP in the same period of treatment of bladder urothelial carcinoma combined with benign prostatic hyperplasia patients with significant curative effect, high safety, does not increase the risk of tumor recurrence and metastasis, and can effectively relieve urinary tract obstruction.