儿童甲状腺疾病在儿科内分泌疾病中居首位。原发性甲状腺功能低减症中的先天性甲状腺激素合成障碍少见,尤其同胞兄妹均患病更属罕见。例1.男,5岁。第1胎第1产,足月顺产,出生体重2.75%,无围产窒息。生后半月余可见皮肤和巩膜黄染,持续约4个月后逐渐消退。皮肤逐渐粗糙,出 Children with thyroid disease in pediatric endocrine disease in the first place. Congenital thyroid hormone synthesis in primary hypothyroidism disorder rare, especially siblings are more common disease. Example 1. Male, 5 years old. The first birth of the first child, full-term birth, birth weight 2.75%, no perinatal asphyxia. Half a month after birth can be seen in the skin and sclera yellow dye, continued for about 4 months after gradually subsided. Skin gradually rough, out