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本文应用荧光分光分析法,测定了流行性出血热(EHF)病人不同病期血浆中NE和E的含量。结果表明:发热期、低血压少尿期和多尿期时,患者去甲肾上腺素(NE)含量显著高于正常人;肾上腺素(E)的含量在发热期和低血压少尿期时与正常人相比也有显著性差异。提示NE和E参与发热、低血压、少尿期的发病过程,且具有重要意义。进一步为临床应用β-受体阻断剂治疗提供了理论依据。同时,提示在低血压、少尿期合并应用α-受体阻断剂对改善肾脏血液循环可能更为有效。
In this paper, fluorescence spectrometry was used to determine the levels of plasma NE and E in patients with epidemic hemorrhagic fever (EHF) at different stages. The results showed that the content of norepinephrine (NE) was significantly higher in patients with fever period, oliguria period and polyuria period than those in normal people. The content of epinephrine (E) in the period of fever and oliguria of hypotension There are also significant differences between normal people. It suggests that NE and E are involved in the pathogenesis of fever, hypotension and oliguria, and are of great significance. Further provide a theoretical basis for the clinical application of β-blocker therapy. At the same time, suggesting that in the hypotension, oliguria period combined application of α-blockers on the improvement of renal blood circulation may be more effective.