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患者男,60岁。右食指近端桡侧不规则污褐色丘疹、斑块、结节1年余,加重2个月。皮损组织病理示:表皮全层细胞排列紊乱,可见不典型角质形成细胞,有明显异型性及角化不良细胞,真皮浅层可见大量淋巴细胞及慢性炎性细胞浸润。诊断:鲍温病。经CO2激光祛除皮损疣状斑块结节,炭化至肿块基底部上方,即行20%5-氨基酮戊酸(ALA)光动力疗法(PDT)治疗,共治疗4次。皮损完全恢复,随访20个月,未见新的皮疹发生。
Male patient, 60 years old. The right index finger near the radial side irregular stained papules, plaques, nodules more than 1 year, increased 2 months. Histopathological examination showed that the cells in the epidermis were disordered, showing atypical keratinocytes, obvious atypia and keratinocytes, and a large number of infiltrating lymphocytes and chronic inflammatory cells in the dermis. Diagnosis: Bowen’s disease. C02 laser cut skin lesions verrucous plaque nodules, carbonized to the top of the mass base, which is 20% 5-aminolevulinic acid (PDT) phototherapy (PDT) treatment, a total of 4 times. Skin lesions completely restored, followed up for 20 months, no new rash occurred.