目的 :探讨提高嗜铬细胞瘤患者围手术期安全性的措施。方法 :对 15例嗜铬细胞瘤患者 ,术前采用选择性α1受体阻滞剂多沙唑嗪控释片 (可多华 )控制高血压 ;11例患者采用 3DDCEMRA进行肿瘤定位 ;术中均采用联合高容量血液稀释 (AHH)和术中患者自体血回输纠正血容量。结果 :除 1例持续性高血压患者需联合钙离子拮抗剂和ACEI药物降压外 ,其余患者血压控制均为满意 ;根据 3DDCEMRA定位选择手术径路者均顺利完成手术 ;AHH联合术中自体血回输使 14例患者避免了异体输血。结论 :本文围手术期处理改进 ,可多华可明显减少药物的不良反应 ;采用 3DDCEMRA进行肿瘤定位 ,可增加手术安全性 ;AHH联合术中自体血回输可减少医疗成本和异体输血 ,以及由此而引起的并发症。 Objective: To explore the measures to improve perioperative safety of patients with pheochromocytoma. Methods: Fifteen patients with pheochromocytoma were treated with doxazosin controlled release (α-adrenergic blocker) preoperatively for hypertension. Eleven patients were treated with 3DDCEMRA for tumor location. Intraoperatively Blood volume was corrected using combined high volume hemodilution (AHH) and intraoperative autologous blood transfusion. Results: The blood pressure was controlled satisfactorily in all the patients with persistent hypertension except for the combination of calcium antagonists and ACEIs. All patients underwent surgery according to 3DDCEMRA, and AHH combined with intraoperative autologous blood Fourteen patients were prevented from having allogeneic transfusions. CONCLUSIONS: The perioperative management is improved in this paper, Kehuahua can significantly reduce adverse drug reactions; using 3DDCEMRA for tumor localization can increase the safety of surgery; AHH combined with intraoperative autologous blood transfusion can reduce medical costs and allogeneic blood transfusion, and by This caused complications.