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作者在第一报中报导了超声波对含孕酮混悬液的分散作用,叙述了实驗方法及一些影响分散的因素。本文再报告黏度、温度、压力等的影响,同时报导了对数种甾类药物分散的难易。本报告中所用仪器与测定方法同第一报。 1.黏度影响:文献指出黏度不利于分散。作者用0.5％甲基纖维(分低、高、中等黏度三种)及0.5％羧基甲基纖維(分100、400、1,500、4,000厘泊四种)七种溶液,各加入孕酮100mg(过200
In the first paper, the authors report the dispersion of ultrasound on progesterone-containing suspensions, and describe the experimental methods and some factors that influence dispersion. This article reports the effects of viscosity, temperature, pressure, etc., and reports on the ease of dispersion of several steroids. The instruments and methods used in this report are the same as the first report. 1. Viscosity effects: the literature pointed out that the viscosity is not conducive to dispersion. The authors used seven kinds of solutions of 0.5% methylcellulose (three kinds of low, high and medium viscosity) and 0.5% carboxymethylcellulose (four kinds of 100, 400, 1,500 and 4,000 cp) Over 200