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目的 研究红毛五加多糖对人胃癌细胞、人胚腱细胞及正常人外周血淋巴细胞的选择性抑制作用特点。方法 采用细胞形态学方法和MTT法。结果 该多糖选择性地抑制了胃癌细胞的活性和功能状态 ,而对人胚腱细胞影响甚微 ,对正常人外周血淋巴细胞无影响。结论 该多糖选择性地抑制了人胃癌细胞 ,用于肿瘤的防治可能较为安全。
Objective To study the selective inhibitory effect of Acanthopanax senticosus polysaccharides on human gastric cancer cells, human embryonic nevus cells and normal human peripheral blood lymphocytes. Methods Cell morphology and MTT assays were used. Results The polysaccharide selectively inhibited the activity and functional status of gastric cancer cells, but had little effect on human embryonic nevus cells and had no effect on normal human peripheral blood lymphocytes. Conclusion The polysaccharide selectively inhibits human gastric cancer cells and may be used for the prevention and treatment of cancer.