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目的通过回顾性分析特殊情况紧急抢救时单采血小板ABO同型输注与异型输注2组病例,探讨单采血小板ABO非同型输注的必要性和可行性。方法统计邯郸地区8家医院非同型紧急抢救输注单采血小板情况,统计2014年12月-2015年11月单采血小板ABO异型输注率,分析比较单采血小板ABO同型和异型输注2组病例的临床输注指征及输注效果评价。结果共输注单采血小板804袋,ABO同型输注780袋,输注率97.01%,异型输注24袋,输注率2.99%;同型输注有效率75.26%,异型输注有效率41.67%,2组病例输注有效率差别比较有统计学意义。排除非免疫因素,同型输注有效率80.08%,异型输注有效率62.5%,2组病例输注有效率比较差异无统计学意义。结论单采血小板输注有效率ABO异型输注低于ABO同型输注,但排除非免疫因素,2组病例输注无显著性差异,因此,特殊情况紧急抢救时,ABO异型输注是必要的、可行的。
Objective To investigate the necessity and feasibility of non-homogenous ABO noninvasive transfusion with retrograde analysis of two groups of ABO isotype infusion and heterotypic infusion in the case of special emergency rescue. Methods Statistical analysis was conducted on the emergency rescue of single platelet transfusions in 8 hospitals in Handan. The rate of ABO heterotopic injection of apheresis platelets from December 2014 to November 2015 was statistically analyzed. Indications of clinical transfusion and evaluation of infusion effect. Results A total of 804 bags of apheresis platelets were transfused with 780 bags of ABO homogenate, the rate of transfusion was 97.01%, and 24 bags of heterotrophic transfusion with a rate of 2.99%. The effective rate of homologous transfusion was 75.26% and that of heterotopic transfusion was 41.67% The differences of effective rate of infusion between the two groups were statistically significant. Excluding non-immune factors, the same type of infusion efficiency 80.08%, effective rate of heterotypic infusion of 62.5%, two groups of patients with no significant difference in the efficiency of infusion. CONCLUSIONS: ABO isotype infusion is less effective than ABO isotype infusion in single platelet transfusions, but noninflammatory factors are excluded and there is no significant difference in infusion between the two groups. Therefore, ABO atypical infusion is necessary for emergency treatment under special circumstances ,feasible.