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目的判断红细胞膜总胆固醇(CEM)含量对急性冠脉综合征的(ACS)预测价值。方法通过对35例稳定型心绞痛组(对照组)与30例急性冠脉综合征组CEM的含量测定,并与血脂和C反应蛋白(CRP)比较,来评判CEM在ACS中的意义。结果CEM和CRP在ACS患者中明显增高,血脂在两组间差异无显著性。结论CEM水平的增高能作为预测易损斑块和ACS的一个新指标,较CRP的优越性有待进一步研究。
Objective To evaluate the predictive value of total cholesterol (CEM) in erythrocyte membrane on acute coronary syndrome (ACS). Methods The CEM levels in 35 patients with stable angina (control group) and 30 patients with acute coronary syndrome (ACS) were determined and compared with those of serum lipids and C-reactive protein (CRP) to evaluate the significance of CEM in ACS. Results CEM and CRP were significantly higher in patients with ACS, blood lipids in the two groups showed no significant difference. Conclusion The increase of CEM level can be used as a new index for predicting vulnerable plaque and ACS. The superiority of CRP remains to be further studied.