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目的探讨氯沙坦氢氯塞嗪联合比索洛尔治疗老年急性心力衰竭的临床效果。方法将100例患者分为治疗组和对照组,各50例,对照组采用常规治疗,治疗组在对照组常规治疗的基础上加用氯沙坦氢氯塞嗪联合比索洛尔,观察两组患者的治疗效果。结果治疗组治疗前后的心衰氨基末端脑内肽前体、左室射血分数、美国纽约心脏病学会(NT-proBNP、LVEF、NYHA)分级指标改善优于常规治疗组,治疗组的总有效率为91.66%,而对照组为82.00%,P<0.05,差异具有统计学意义。结论氯沙坦氢氯塞嗪联合比索洛尔疗效好。
Objective To investigate the clinical effects of losartan hydrochloride and bisoprolol in the treatment of elderly patients with acute heart failure. Methods 100 patients were divided into treatment group and control group, 50 cases in each group. The control group was treated with conventional therapy. The treatment group was given Losartan Hydrochlorothiazide combined with Bisoprolol on the basis of conventional treatment. Patient’s therapeutic effect. Results Before and after treatment, the levels of amino-terminal pro-brain natriuretic peptide, left ventricular ejection fraction, NT-proBNP (LVEF, NYHA) in the treatment group were better than those in the conventional treatment group Efficiency was 91.66%, while the control group was 82.00%, P <0.05, the difference was statistically significant. Conclusion Losartan Hydrochlorothiazide combined with bisoprolol has good curative effect.