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为探讨二探术时残余肿瘤直径≤0.5cm的上皮性卵巢癌患者腹腔内注射α干扰素的疗效及毒性反应做下述研究。 列入研究患者条件:肿瘤局限于腹腔,包括腹膜后病灶。首次化疗部分缓解或未完全缓解,化疗后行二探术能达到残余肿瘤最大直径≤0.5cm者45例;首次化疗完全缓解,疑为肿瘤复发二探时残余肿瘤最大直径≤0.5cm者45例。腹腔内注射α干扰素的剂量为5000万U,每周1次,共12周。若患者
In order to investigate the efficacy and toxicity of intra-abdominal injection of IFN-α in patients with epithelial ovarian cancer with residual tumor diameter ≤0.5cm during the second exploration, the following studies were performed. Inclusion of patient conditions: The tumor is confined to the peritoneal cavity, including retroperitoneal lesions. The first chemotherapy was partly relieved or not completely relieved. After the second chemotherapy, 45 patients with the largest residual tumor ≤0.5cm could be achieved in the first chemotherapy. The first chemotherapy was completely relieved and the second was the suspected tumor recurrence. . Intraperitoneal injection of interferon alpha dose of 50 million U, once a week for a total of 12 weeks. If the patient