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目的评价甲壳素粉状敷料对皮肤浅部切割伤的止痛作用及临床应用的安全性。方法将60例浅部切割伤病人随机分为两组,敷用云南白药组(对照组)30例,敷用甲壳素粉状敷料组(实验组)30例,临床观察7 d并评价其临床效果及安全性。结果实验组止痛疗效总有效率为96.66%,对照组100%,两组比较无统计学意义(P>0.05);实验组疼痛起效时间有效率为80%,对照组96.66%(P>0.05);另外,两组间红肿消失率、渗液消失率、伤口愈合率、化脓性感染发生率比较无显著差异(P>0.05)。无不良事件发生。结论甲壳素粉状敷料具有良好的止痛效果,且临床应用安全。
Objective To evaluate the analgesic effect and clinical application of chitin powder dressing on cutaneous superficial skin lesions. Methods Sixty cases of superficial incision wounds were randomly divided into two groups. 30 cases were treated with Yunnan Baiyao group (control group), 30 cases were treated with chitin powder dressing group (experimental group), and were observed for 7 days and evaluated Clinical effect and safety. Results The total effective rate of pain relief in experimental group was 96.66% and that in control group was 100%, there was no significant difference between the two groups (P> 0.05). The effective rate of pain onset time was 80% in experimental group and 96.66% in control group (P> 0.05 ); In addition, there was no significant difference in the rate of disappearance of infiltration, disappearance of exudate, wound healing rate and purulent infection between the two groups (P> 0.05). No adverse events occurred. Conclusion Chitin powder dressing has a good analgesic effect and clinical application is safe.