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用放免法(RIA)测定了56例冠心病充血性心力衰竭(CHF)不同心功能(NYHAⅡ~Ⅲ级)状态下治疗前后血浆血栓素B2(TXB2)、内皮素(ET)、脂质过氧化物(LPO)的浓度及临床心功能的变化及应用益气活血利湿方药或西药常规治疗后的变化。结果显示治疗前心功能在Ⅱ级、Ⅲ级的CHF病人的ET、TXB2、LPO值明显增高,其含量与CHF的严重程度有明显的一致性。同时显示经治疗后CHF心功能改善,ET、TXB2明显降低,益气活血利湿方疗效较常规西药治疗明显为优
Radioimmunoassay (TXB2), endothelin (ET), and lipid peroxidation in 56 patients with congestive heart failure (CHF) with different cardiac function (NYHA class III to III) were measured by radioimmunoassay (RIA). Concentration of substance (LPO) and changes in clinical heart function and changes after application of Yiqi Huoxue Lishi Recipe or Western medicine conventional treatment. The results showed that the ET, TXB2, and LPO values of CHF patients with grade II and III cardiac function before treatment were significantly higher, and their levels were significantly consistent with the severity of CHF. At the same time, after treatment, the improvement of CHF cardiac function, ET and TXB2 were significantly reduced, and the therapeutic effect of Yiqi Huoxue Lishi Decoction was significantly better than that of conventional western medicine.