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采用卫生学检验的方法,对不同产地、不同商品规格和不同贮藏期全蝎商品中的大肠杆菌、沙门氏菌、杂菌、霉菌和酵母菌进行了检测。结果:29份全蝎样品均未检出大肠杆菌和沙门氏菌;但是,染杂菌率达100％,淡全蝎的染杂菌率高于咸全蝎的2.1倍;在29份全蝎样品中,染杂菌超过10~5/g的药材占6.9％。霉菌染菌率达72.4％,其中咸全蝎染霉菌率较淡全蝎高15％,染霉菌的不合格率高达27.55％;经鉴定,与人类疾病有关的病原菌有链格孢Alternalia neesex Wallroth、烟曲霉菌Aspergillus fumigatus Fresenius、诺卡氏菌Nocarcia sp.、紫色毛癣菌Trico-phyton violaceum Sabouraud等4种。建议有关药品标准中增加对动物类药材的部分卫生学检查项目,以控制其质量,并加强对商品的贮藏和保管,以减少污染。由于咸全蝎易染致病菌,中国药典应取消咸全蝎商品或增加对咸全蝎的卫生学检验指标,以保证临床用药的安全和有效。
By means of hygiene tests, E. coli, Salmonella, mixed bacteria, molds, and yeasts in products of different origins, different product specifications, and different storage periods were tested. Results: Escherichia coli and Salmonella were not detected in all 29 samples. However, the rate of infected bacteria was 100%, and the percentage of infected bacteria was less than 2.1 times of that of whole bran; in 29 samples of total caries. , The proportion of medicinal materials with more than 10~5/g of bacteria was 6.9%. The mold infection rate reached 72.4%, among which the salty fungal infection rate was 15% higher than that of the whole plant, and the unqualified rate of the mold was 27.55%. After identification, Alternne neesex Wallroth, the pathogen associated with human diseases, was identified. Aspergillus fumigatus Fresenius, Nocarcia sp., Trico-phyton violaceum Sabouraud and other four species. It is suggested that some hygiene inspection items for animal medicines be added to relevant drug standards in order to control their quality and to strengthen the storage and storage of commodities so as to reduce pollution. Since Xianquanyi is susceptible to pathogenic bacteria, the Chinese Pharmacopoeia should abolish the Xianquanquan commodities or increase the hygiene inspection indicators of Xianquanquan in order to ensure the safety and effectiveness of clinical drug use.