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目的对玉溪市适龄儿童麻疹疫苗(MV)常规免疫后抗体水平进行评价,为今后制定相关策略提供科学依据。方法对1958名适龄儿童血清标本采用ELISA法检测麻疹抗体IgG。结果麻疹抗体阳性率93.97%,几何平均滴度(GMT)1∶706.78,不同年龄抗体阳性率差异有统计学意义(χ2=6.07、P<0.05),GMT差异无统计学意义;不同地区抗体阳性率、GMT差异均有统计学意义(χ2=30.1,F=10.22、P<0.01),不同年度抗体阳性率和GMT差异均有统计学意义(χ2=28.95,F=19.78、P<0.01)。结论玉溪市适龄儿童麻疹抗体水平较高,并形成了有效免疫屏障。
Objective To evaluate the antibody level of measles vaccine (MV) after routine immunization in Yuxi City, and to provide a scientific basis for formulating relevant strategies in future. Methods Serum samples from 1958 school-age children were tested for measles IgG by ELISA. Results The positive rate of measles antibody was 93.97%, and the geometric mean titer (GMT) was 1:706.78. The positive rate of antibody at different ages was statistically significant (χ2 = 6.07, P <0.05), but there was no significant difference in GMT between the two groups (Χ2 = 30.1, F = 10.22, P <0.01). The positive rates of antibody and GMT in different years had statistical significance (χ2 = 28.95, F = 19.78, P <0.01). Conclusion The measles antibody level of Yixi school-age children is high, and an effective immune barrier is formed.