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目的对开同(复方α-酮酸片)治疗维持性血液透析患者营养不良的临床疗效进行探讨。方法 68例维持性血液透析患者,利用数字表法将其随机分成观察组与对照组,每组34例,给予观察组患者开同治疗,给予对照组患者常规营养治疗。对比分析两组患者治疗前后营养情况。结果治疗前两组患者各观察指标差异无统计学意义(P>0.05);治疗后观察组三酰甘油、总胆固醇水平显著低于对照组(P<0.05),而转铁蛋白、前白蛋白、血清白蛋白、血红蛋白水平较对照组升高明显,差异具有统计学意义(P<0.05)。结论治疗维持性血液透析时使用开同,可显著改善患者营养状况,提高患者生存质量,应在临床中推广应用。
Objective To investigate the clinical efficacy of Kaitong (compound α-ketoacid tablets) in the treatment of malnutrition in maintenance hemodialysis patients. Methods Sixty-eight patients with maintenance hemodialysis were randomly divided into observation group and control group by digital table method, with 34 cases in each group. The patients in observation group were treated with the same therapy and the patients in the control group were given routine nutrition therapy. Compare the nutritional status of the two groups before and after treatment. Results There was no significant difference between the two groups before treatment (P> 0.05). After treatment, the levels of triglyceride and total cholesterol in the observation group were significantly lower than those in the control group (P <0.05), while the transferrin, prealbumin , Serum albumin, hemoglobin levels increased significantly compared with the control group, the difference was statistically significant (P <0.05). Conclusions The treatment of maintenance hemodialysis with the use of the same, can significantly improve the nutritional status of patients and improve the quality of life of patients should be popularized and applied in the clinic.