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目的：比较血脂康和辛伐他汀用于治疗初期高脂血症的作用。方法：108名患有初期脂血症的病人随机分为两组。第一组53名患者每日服4粒血脂康胶囊（1.2 g/天）共服八周；第二组55名患者每日服辛伐他汀10 mg共服八周。八周后的血脂水平与各组的基线比较。结果：第一组患者的血清总胆固醇（TC），低密度脂蛋白（LDL）和甘油三酯（TG）分别降低23.0%，28.0%和28.1%（P<0.001）；第二组分别降低23.3%，29.5%和29.5%（P<0.001）。服药后血清高密度脂蛋白（HDL）胆固醇血脂康组升高5.0%（P>0.05）。辛伐他汀组升高14.3%（P<0.01）。两组间TC，LDL胆固醇，TG和HDL胆固醇的变化无显著性差异。血脂康的副作用比辛伐他汀的弱。结论：中国产的血脂康为一种安全，有效和耐受性良好的血脂调节剂。
Objective: To compare the effects of Xuezhikang and simvastatin on the treatment of initial hyperlipidemia. Methods: 108 patients with initial lipidemia were randomly divided into two groups. The first group of 53 patients took 4 capsules of Xuezhikang (1.2 g / day) for 8 weeks. The second group of 55 patients took 10 mg of simvastatin daily for 8 weeks. Blood lipid levels after eight weeks were compared to the baseline for each group. Results: In the first group, serum total cholesterol (TC), low density lipoprotein (LDL) and triglyceride (TG) decreased by 23.0%, 28.0% and 28.1% (P <0.001) %, 29.5% and 29.5% (P <0.001). After taking the drug serum high-density lipoprotein (HDL) cholesterol Xuezhikang increased 5.0% (P> 0.05). Simvastatin group increased by 14.3% (P <0.01). TC, LDL cholesterol, TG and HDL cholesterol changes between the two groups no significant difference. Xuezhikang side effects than simvastatin weak. Conclusion: Chinese-made Xuezhikang is a safe, effective and well-tolerated blood lipid regulators.