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目的 :研究尿道压力分布图 (UPP)对良性前列腺增生 (BPH)患者α肾上腺素能受体阻滞剂治疗效果的预测。方法 :用改良苄胺唑啉 U PP试验将 BPH患者分为阳性及阴性组 ,比较 U PP图诸参数之差异。结果 :143例 BPH患者行改良苄胺唑啉 U PP试验 ,阳性 6 4例 ,占全部病例 (4 5 7例 )的 14.0 %。资料完整者阳性组 (38例 )及阴性组 (2 8例 )试验前最大尿流率(Qmax,m l/s)及 UPP诸参数无显著性差异 (P>0 .0 5 ) ,阳性组 Qmax增加、U PP诸参数减少有显著性差异 (P<0 .0 1)。阳性组试验前后相比膀胱颈压及前列腺部压力降低低于膜部 ,试验后此两处压力相对值增高。 结论 :用 UPP图形不能代替苄胺唑啉U PP试验来预测 BPH患者 α受体阻滞剂治疗效果 ,BPH伴功能性梗阻者对 α受体阻滞剂最敏感区是远段尿道括约肌
PURPOSE: To study the predictive value of UPP in the treatment of α-adrenergic blockers in patients with benign prostatic hyperplasia (BPH). Methods: BPH patients were divided into positive and negative groups by modified benzylazoline U PP test. The differences of U PP parameters were compared. Results: 143 cases of BPH patients underwent modified benzylazoline U PP test, positive 64 cases, accounting for 14.0% of the total cases (477 cases). There was no significant difference in maximum flow rate (Qmax, ml / s) and UPP parameters between positive group (38 cases) and negative group (28 cases) with positive data (P> 0.05) Increase, U PP parameters reduced significantly (P <0. 01). Compared with the bladder neck pressure and prostate pressure before and after the positive group test lower than the membrane, after the test the relative pressure of the two increased. CONCLUSION: UPP pattern can not be used to replace the benzylazoline U PP test to predict the effect of α-blocker in patients with BPH. The most sensitive area to BPH with functional blockers is distal urethral sphincter