论文部分内容阅读
目的探讨血浆治疗重症手足口病的疗效。方法对开封市儿童医院手足口病重症病区2010年3月至2010年11月收治的210例重症手足口病患儿作为观察对象,随机分为两组,两组均按2010年卫生部颁发的治疗方案,予脱水降颅压,抗病毒,必要时退热,抗感染等治疗,出现呼吸衰竭,胸片提示肺水肿,给予呼吸机支持,其中治疗组在此基础上给予血浆10 ml/(kg.d)连用2～3 d,对照组给予静注人血免疫球蛋白(IVIG)1 g/(kg.d),连用2 d。结果治疗组治愈100%,对照组治愈率99.23%,两组在临床症状消失时间、住院天数等各项指标上,经统计学处理,差异无显著性(P>0.05)。在住院费用上有显著差异(P<0.01)。结论血浆与大剂量IVIG治疗重症手足口病疗效相当,应用血浆治疗能显著降低住院费用。
Objective To investigate the effect of plasma on severe hand-foot-mouth disease. Methods A total of 210 severe HFMD patients admitted to Kaifeng Children’s Hospital from March 2010 to November 2010 were randomly divided into two groups according to the standard of Ministry of Health Of the treatment options, to dehydration reduce intracranial pressure, anti-virus, if necessary, antipyretic, anti-infective treatment, respiratory failure, chest X-ray prompted pulmonary edema, ventilator support, in which the treatment group on the basis of plasma 10 ml / (kg.d) for 2 ~ 3 days. The control group was given IVIG 1 g / (kg · d) for 2 days. Results The cure rate was 100% in the treatment group and 99.23% in the control group. There was no significant difference (P> 0.05) between the two groups in the clinical symptoms disappearance time and hospitalization days and other indicators. The hospitalization costs were significantly different (P <0.01). Conclusions Plasma and high-dose IVIG are effective in treating HFMD. Application of plasma therapy can significantly reduce hospitalization costs.