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目的 :探讨乌三颗粒提高腹水型荷瘤小鼠的生存质量。方法 :昆明种小鼠腹腔分别接种腹水型S180 和肝癌 ( He PA)癌性腹水 ,用乌三颗粒灌胃 1 0天 ,记录各组小鼠死亡时间 ,统计生存期延长率。结果 :乌三颗粒在 1 6.0 g/kg剂量下 ,对 S180 和 He PA癌性腹水型小鼠生存期延长率分别达 5 5 %和 5 7%以上。结论 :乌颗粒能明显延长恶性肿瘤小鼠的生存期。
Objective: To investigate the effect of Wu San Granule on improving the quality of life of ascites-bearing mice. METHODS: Kunming mice were inoculated intraperitoneally with ascites type S180 and hepatocellular carcinoma (He PA) ascites. Uzbekio granules were intragastrically administered for 10 days. The death time of each group was recorded and the survival rate was calculated. Results: The survival rate of Wusan granules at the dose of 16.0 g/kg for S180 and He PA cancerous ascites mice reached 55% and 57% respectively. Conclusion: Wu granule can significantly prolong the survival period of malignant tumor mice.