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多数重型再生障碍性贫血(SAA)的发病与干细胞免疫损伤有关,其诊断根据外周血象三少和骨髓增生减低。若无骨髓移植供体,免疫抑制剂如环孢菌素 A(CyA)、大剂量甲基强的松龙(HDMP)、抗胸腺细胞球蛋白(ATG)等已证实也是治疗 SAA 的有效手段。近年研究发现绝大多数 SAA 患者抑制性 T
The incidence of most severe aplastic anemia (SAA) and stem cell immune damage, the diagnosis based on peripheral blood count less three and myelodysplasia decreased. In the absence of donor bone marrow transplantation, immunosuppressive agents such as cyclosporin A (CyA), high-dose methylprednisolone (HDMP), anti-thymocyte globulin (ATG) have also proved to be an effective treatment for SAA. Recent studies found that the vast majority of SAA patients with inhibitory T