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本研究分别应用放免法、定量凝固技术、放免法及凝胶空斑法测定60例急性非淋巴细胞性白血病患者蛋白C抗原（PC：Ag）、蛋白C活性（PC：A）、抗凝血酶Ⅲ抗原（ATⅢ：Ag）和抗凝血酶Ⅲ活性（ATⅢ：A）。结果显示M_3未缓解组PC：A（39．75±25．92）比M_3完全缓解组（73．70±32．71）及正常对照组（80．90±20．66）均低（P＜0．05）；M_(1，2，4－6)未缓解组ATⅢ：sA及ATⅢ：Ag（63．68±23．90，22．92±4．76）比1_(1，2，4－6）完全缓解组（81．7±20．75，27．47±6．44）及正常对照组（84．64±16．31，29．51±3．48）均低（P＜0．05）。提示PC及ATⅢ在急非淋不同亚型的凝血紊乱中起作用，且与它们是否缓解有关。
In this study, radioimmunoassay, quantitative coagulation techniques, radioimmunoassay, and gel plaque assay were used to determine protein C antigen (PC:Ag), protein C activity (PC:A), and anticoagulation in 60 patients with acute nonlymphocytic leukemia. Enzyme III antigen (ATIII: Ag) and antithrombin III activity (ATIII: A). The results showed that PC:A (39.75±25.92) in the M_3 non-remission group was lower than the M_3 complete remission group (73.70±32.71) and the normal control group (80.90±20.66) (P< 0.05); M_(1,2,4-6) unremission group ATIII:sA and ATIII:Ag(63.68±23.90, 22.92±4.76) vs 1_(1,2,4 -6) The complete remission group (81.7±20.75, 27.47±6.44) and the normal control group (84.64±16.31, 29.51±3.48) were all low (P<0 .05). It is suggested that PC and ATIII play a role in the coagulation disorder of different subtypes of acute non-lymphocin, and are related to whether they are relieved.