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目的探讨儿童颅咽管瘤显微外科治疗的手术方法、手术入路和治疗效果。方法回顾性分析33例儿童颅咽管瘤患者显微外科治疗的临床资料。结果33例中肿瘤全切除30例,近全切除3例,无手术死亡及严重并发症,近全切者术后辅助立体定向放射治疗。31例获随访17月~8.1年,平均4.8年。效果良好者28例,需生活照顾者3例,MRI/CT复查未见肿瘤复发。结论显微手术切除肿瘤是儿童颅咽管瘤有效的治疗措施;额颞-眶入路能明显缩短到达肿瘤的距离,能显著提高颅咽管瘤手术切除效果。
Objective To investigate the surgical treatment, surgical approach and therapeutic effect of microsurgical treatment of craniopharyngioma in children. Methods Retrospective analysis of 33 cases of children with craniopharyngioma microsurgery clinical data. Results Totally 33 cases of tumor resection in 30 cases, nearly total resection in 3 cases, no operative mortality and serious complications, nearly total resection assisted stereotactic radiotherapy. 31 cases were followed up for 17 months to 8.1 years, an average of 4.8 years. 28 cases of good effect, 3 cases of life caregivers, MRI / CT review no tumor recurrence. Conclusions Microsurgery resection of tumor is an effective treatment for craniopharyngioma in children. Frontotemporal orbital approach can significantly shorten the distance to the tumor and can significantly improve the surgical outcome of craniopharyngioma.