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对４７例糖尿病（ＤＭ）患者及３５例性别、年龄相当的正常对照者行９９ｍＴｃ－ＤＴＰＡ动态显像和双能Ｘ线法腰椎２—４骨密度测定。结果表明，肾功能轻度与重度受损的患者骨密度（ＢＭＤ）同龄百分比值低于对照组（Ｐ＜０．０５和Ｐ＜０．０１）。重度肾功能受损的ＤＭ患者中，ＢＭＤ减低较其他ＤＭ患者严重，提示严重糖尿病肾脏病变将导致骨质疏松。因此，对肾功能受损的ＤＭ患者进行骨质疏松的防治非常必要，同时保护ＤＭ患者的肾功能也将是预防骨质疏松的有效方法。
99mTc-DTPA dynamic imaging and dual-energy X-ray lumbar spine 2-4 bone density were measured in 47 DM patients and 35 normal and age-matched controls. The results showed that patients with mild and severe renal impairment had lower BMD percentage at the same age (P <0.05 and P <0.01). Among DM patients with severe renal impairment, the decrease in BMD is more severe than in other DM patients, suggesting that severe diabetic nephropathy leads to osteoporosis. Therefore, the prevention and treatment of osteoporosis in DM patients with impaired renal function is necessary, and at the same time to protect the renal function of DM patients will also be an effective way to prevent osteoporosis.