1987年,H_2-拮抗剂雷尼替丁再次是世界上第一、第二畅销药品。估计雷尼替丁的营业额为14.79亿美元,西咪替丁的营业额为11.32亿美元。 1987年,世界上最畅销的15个产品按估计营业额(亿美元)排列如下: 新排上最畅销的头50个产品之列的产品有:葛兰素公司的广谱头孢菌素头孢他啶(ceftazidime,商品名:Fortum),Merrell Dow公司的抗组胺药特非那定(terfenadine,商品名:Seldane),威尔康公司的抗疱疹 In 1987, ranitidine, the H 2 -agonist, was once again the first and second best-selling drug in the world. Turnover of ranitidine is estimated at $ 1,479 million and cimetidine at $ 1,132 million. In 1987, the top 15 best-selling products in the world were quoted at the estimated turnover of $ 100 million: The top 50 best-selling products in the new row are: Glaxo’s broad-spectrum cephalosporin ceftazidime ceftazidime, trade name: Fortum), antiretroviral drug terfenadine (product name: Seldane) from Merrell Dow Company, anti-herpes