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目的研究高良姜有效部位对高脂饲料联合链脲佐菌素(STZ)-烟酰胺诱导的二型糖尿病(T2DM)小鼠血糖的影响。方法采用高脂饲料联合STZ-烟酰胺诱导形成T2DM小鼠模型,研究高良姜有效部位对T2DM小鼠血糖的影响。结果 T2DM小鼠给予该有效部位200 mg/kg 4周后,小鼠的随机血糖水平显著下降,糖耐量得到了明显改善。结论高良姜有效部位有较好的降血糖作用。
Objective To study the effect of galangal effective fraction on the blood glucose of high fat diet combined with streptozotocin (STZ) - nicotinamide induced type 2 diabetes mellitus (T2DM) mice. Methods T2DM mice were induced by high fat diet combined with STZ-nicotinamide to study the effects of galangal effective sites on blood glucose in T2DM mice. Results After T2DM mice were given 200 mg / kg of the effective site for 4 weeks, the mice had a marked decrease in random blood glucose levels and a marked improvement in their glucose tolerance. Conclusion galangal effective site has a good hypoglycemic effect.