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CML是一个包含了2至3个监床阶段的骨髓多能干细胞克隆失常症，先后出现慢性期（CP）、加速期（AP）和急变期（BC）。慢性粒细胞性白血病（CML）治疗虽有不少进展，但患者的生存期并无明显延长。大部分患者最终发生慢粒急变，病人一旦出现急变，预后极差，这是70%以上慢粒病人死
CML is a bone marrow pluripotent stem cell cloning disorder that involves 2 to 3 beds. There are chronic phase (CP), accelerated phase (AP) and blast crisis (BC). Although there have been many advances in the treatment of chronic myelogenous leukemia (CML), the survival of patients has not been significantly prolonged. The majority of patients eventually develop chronic granulomal transformation. Once the patient undergoes a sudden change, the prognosis is extremely poor, which is more than 70% of patients with chronic granulocytosis die.