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子宫平滑肌的收缩性和其它的平滑肌一样,与细胞浆中游离钙的浓度直接有关。促使子宫收缩引起钙浓度的增高,抑制子宫收缩则使之下降。子宫肌细胞浆内游离钙的浓度主要受两个方面的来源所调节。一个是细胞外钙池,这部分钙大多数结合在细胞表面膜上,膜上可能有两种特殊的钙通道,一种是电位敏感管道,另一种为受体控制管道,可允钙离子从细胞外钙池进入胞浆内。另一个胞浆内钙的来源是细胞内钙库,由结合在胞内结
Uterine smooth muscle contraction, like other smooth muscle, is directly related to the concentration of free calcium in the cytoplasm. Promote uterine contraction caused by increased calcium concentration, inhibition of uterine contractions make it down. The concentration of intracellular free calcium in myometrium is regulated mainly by two sources. One is the extracellular calcium pool, most of this part of the calcium binding on the cell surface membrane, the membrane may have two special calcium channels, one is potential-sensitive pipelines, the other for the receptor control of the pipeline, allowing calcium ions Into the cytoplasm from the extracellular calcium pool. Another source of intracytoplasmic calcium is the intracellular calcium pool, which is bound by intracellular junctions