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【目的】探讨在组织间永久性植入放射微粒(碘125)治疗恶性肿瘤的方法和疗效。【方法】对诊断明确的36例恶性肿瘤患者,在手术直视下或B超引导下将碘125粒子永久性植入瘤体内或淋巴转移途径处,进行内放射治疗。【结果】肿瘤完全消退或部分消退(CR+PR)28例,占77.8%(28/36)。患者的血清肿瘤标志物数值明显下降;治疗过程中无明显不良反应。【结论】组织间永久性植入放射微粒(碘125)治疗实体恶性肿瘤,近期疗效显著,治疗操作简单、安全,损伤小,可以作为实体恶性肿瘤的综合治疗方法之一。
【Objective】 To investigate the method and efficacy of permanent implantation of radioactive particles (Iodine 125) in the treatment of malignant tumors. 【Method】 Thirty-six patients with malignant tumor were enrolled in this study. The iodine 125 particles were permanently implanted into the tumor or lymphatic metastasis under the direct vision of surgery or B-ultrasound. 【Results】 28 cases (77.8%) had complete or partial regression of CR + PR (28/36). Patients with serum tumor markers decreased significantly; no obvious adverse reactions during treatment. 【Conclusion】 The permanent implantation of radioactive particles (Iodine 125) between the tissues for the treatment of solid malignant tumors has obvious curative effect in the near future. The operation is simple, safe and less damaging. It can be used as one of the comprehensive treatment of solid malignant tumors.