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目的:分析引起药物性肝炎的主要病因、临床特点及转归。方法:回顾我院2008年1月～2012年12月收治的139例药物性肝炎的用药情况、临床表现、治疗及转归。结果:导致药物性肝炎的药物多为抗结核药、抗肿瘤药、抗生素、心血管系统用药、中药、口服降糖药、解热镇痛药等,临床表现为发热、乏力、食欲不振、尿黄、皮肤巩膜黄染,预后良好。结论:引起药物性肝炎的药物种类多,临床医务工作者应提高对本病的重视程度及加强用药监管力度。
Objective: To analyze the main etiology, clinical characteristics and prognosis of drug induced hepatitis. Methods: To review the medication, clinical manifestation, treatment and prognosis of 139 cases of drug hepatitis in our hospital from January 2008 to December 2012. Results: Most of the drugs that cause drug-induced hepatitis were anti-TB drugs, antineoplastic drugs, antibiotics, cardiovascular system drugs, traditional Chinese medicine, oral hypoglycemic drugs, antipyretic and analgesic drugs, etc. The clinical manifestations were fever, fatigue, loss of appetite, Yellow, scleral skin yellow dye, the prognosis is good. Conclusion: There are many types of drugs that cause drug-induced hepatitis, and clinical medical workers should pay more attention to this disease and strengthen supervision of drug use.