论文部分内容阅读
目的:了解近年来大肠癌治疗的变迁和疗效。方法:回顾分析我院1991年3月～2001年3月915例结直肠癌手术患者的治疗情况,对比第一个5年和第二个5年的治疗方法的变迁。结果:近5年结直肠癌的1、3、5年生存率较前5年明显提高。而术后的复发率明显减低。近5年来,在手术治疗上,结肠癌伴梗阻急诊手术一期根治切除吻合开展的较为普遍;中低位直肠癌直肠下端肠管切除的长度及保肛手术时肿瘤距肛缘的距离缩短;术后复发或孤立转移,只要条件允许应进行再手术切除。辅助治疗,无论是适应证或方法,均发生了明显的变迁,由过去的较简单的治疗方法转变为放射治疗、化疗治疗、免疫治疗、中医中药治疗等联合的综合治疗。结论:大肠癌的治疗无论在手术治疗上还是辅助治疗上都发生了明显变化而且更趋有效、合理。
Objective: To understand the changes and efficacy of colorectal cancer treatment in recent years. Methods: Retrospective analysis was performed on the treatment of 915 colorectal cancer patients in our hospital from March 1991 to March 2001. The treatment changes in the first 5 years and the second 5 years were compared. Results: The 1-, 3-, and 5-year survival rates of colorectal cancer in recent 5 years were significantly higher than those in the previous 5 years. The postoperative recurrence rate was significantly reduced. In the past five years, in the surgical treatment, the first radical resection and anastomosis of colon cancer with obstructive emergency surgery is more common; the length of the rectal lower rectal resection of the middle and low rectal cancer and the distance between the tumor and the anal margin during sphincter preserving surgery; Recurrence or solitary metastases should be reoperatively removed as long as conditions permit. Adjuvant treatment, whether it is indications or methods, has undergone significant changes, from the simpler treatment in the past into radiation therapy, chemotherapy, immunotherapy, traditional Chinese medicine treatment and other combined treatment. Conclusion: The treatment of colorectal cancer has undergone significant changes both in surgical treatment and adjuvant therapy and has become more effective and reasonable.