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氨噻羧单胺菌素(Aztreonam)对产β—内酰胺酶的流感杆菌、绿脓杆菌和肠杆菌科均有很强的抗菌活性。在酸性和厌氧环境(如脓肿)中,氨噻羧单胺菌素仍具有较好的抗菌活性。该药对革兰氏阳性菌和厌氧菌无抗菌作用。象所有β—内酰胺抗生素一样,氨噻羧单胺菌素干扰细菌细胞壁的生物合成,抑制细胞分裂,从而杀死细菌。该药耐多种β—内酰胺酶,仅为κ_1β—内酰胺酶所破坏。
Aztreonam Amythromycin (Aztreonam) for β-lactamase-producing strains of influenza, Pseudomonas aeruginosa and Enterobacteriaceae have strong antibacterial activity. Ammonia in the acid and anaerobic environment (such as abscess), ammonia ceftazidime still has good antibacterial activity. The drug has no antibacterial effect on Gram-positive bacteria and anaerobic bacteria. Like all beta-lactam antibiotics, amiloxins interfere with the biosynthesis of bacterial cell walls, inhibiting cell division and killing bacteria. The drug resistant to a variety of β-lactamase, κ_1β-lactamase destruction only.