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对121例喉癌患者行喉癌手术及(或)放疗后的甲状腺功能进行观察。结果是:①34%(41/121)的患者在治疗结束后不同时间内出现甲状腺功能减退(甲退);②放疗结合手术治疗者中,同时行甲状腺半切除及未行甲状腺半切除者甲退发生率分别为54%和13%,两者呈高度显著性差异;③术前或术后进行放疗对甲状腺功能的影响无显著差异,且单纯放疗在较短期内对甲状腺功能影响不大,甲退发生率仅约5%;④甲退多发生于治疗结束后2年内,占73%,其余见于治疗后7年内。对此,临床应予以重视。
121 cases of laryngeal cancer patients undergoing laryngeal surgery and (or) thyroid function after radiotherapy were observed. The results were: ① Thirty-four percent (41/121) of the patients had hypothyroidism at different times after the end of treatment (A); ② In the combination of radiotherapy and surgery, concurrent thyroidectomy and thymectomy The incidence rates were 54% and 13%, respectively, the two were highly significant differences; ③ preoperative or postoperative radiotherapy on thyroid function was no significant difference, and radiotherapy alone in the short term has little effect on thyroid function, a Retirement rate of only about 5%; ④ A withdrawal occurred in more than 2 years after the end of treatment, accounting for 73%, the rest found in 7 years after treatment. In this regard, clinical should be taken seriously.