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目的:了解厦门地区静脉吸毒者传染病的感染状况及相关因素,为更有效地预防和控制吸毒人群传染病的感染与传播提供依据。方法:同时收集静脉吸毒者血清1036份和正常人群血清标本874份,进行肝功能、乙肝表面抗原、丙肝抗体、梅毒抗体、艾滋病抗体检测,作对比分析。结果:1036例静脉吸毒者血清标本中,肝功能异常率30.5%;乙肝表面抗原阳性率17.86%;丙肝抗体阳性率55.3%;梅毒抗体阳性率4.5%;艾滋病抗体0.68%;对照实验:874例正常人群,肝功能异常率5.1%,乙肝表面抗原阳性率10.18%,丙肝抗体阳性率2.7%,梅毒抗体阳性率0.8%,艾滋病抗体阳性率为零。两组结果对照的差异性,具有统计学意义。结论:静脉吸毒者肝功能、乙肝、丙肝、梅毒、艾滋病血清学标志物感染率明显高于正常人群,是传染病感染与传播的高危人群。吸毒者的吸毒模式和行为模式是各项传染病感染与传播的主要因素。
Objective: To understand the status of infectious status and related factors of intravenous drug users in Xiamen area, and provide evidence for more effective prevention and control of infection and transmission of infectious diseases among drug users. Methods: 1036 serum samples from intravenous drug addicts and 874 serum samples from normal population were collected for detection of liver function, hepatitis B surface antigens, hepatitis C antibodies, syphilis antibodies and AIDS antibodies for comparative analysis. Results: In 1036 intravenous drug users, the abnormal liver function rate was 30.5%; the positive rate of hepatitis B surface antigen was 17.86%; the positive rate of hepatitis C antibody was 55.3%; the positive rate of syphilis antibody was 4.5%; the AIDS antibody was 0.68% The normal population, abnormal liver function rate of 5.1%, HBsAg positive rate of 10.18%, hepatitis C antibody positive rate of 2.7%, syphilis antibody positive rate of 0.8%, HIV antibody positive rate of zero. The difference between the two groups was statistically significant. Conclusion: The infection rates of liver function, hepatitis B, hepatitis C, syphilis and AIDS serological markers of intravenous drug users are significantly higher than those of normal people, which is a high risk group of people infected and transmitted by infectious diseases. Drug abusers’ patterns of drug abuse and behavior patterns are the main factors that affect the transmission and transmission of various infectious diseases.