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目的:探讨孕晚期膳食营养、25-羟维生素Dn 3（25-（OH）Dn 3）水平与婴儿湿疹的关系，为婴儿湿疹的早期预防提供临床依据。n 方法:选取2017年1—12月在新疆维吾尔自治区人民医院妇产科门诊进行产前检查的妊娠晚期（孕28~40周）孕妇，并住院分娩的365名产妇及其新生儿为研究对象，进行前瞻性研究；对进入队列孕周≥28周的孕妇均需抽取外周静脉血，检测孕妇血清中25-（OH）Dn 3含量，同时对孕妇进行孕期维生素D相关因素及新生儿出生情况的基线调查，对其分娩后进行为期6个月（1个月、3个月、6个月）的母婴随访，观察婴儿湿疹发生情况，进而分析孕晚期女性血清中25-（OH）Dn 3含量高低及孕期膳食营养对婴儿湿疹的作用。n 结果:最终获得完整母婴信息共340对并完成为期6个月的随访，纳入本研究。有229例占62.74%的婴儿发生湿疹，其中51.97%（119/229）的婴儿湿疹集中发生在出生后2~3个月。而Logistic回归结果显示，孕期经常进食牛奶和鸡蛋、进食辛辣食物、孕晚期母血25-（OH）Dn 3水平≤20 ng/ml是影响婴儿湿疹的危险因素（n P<0.05），孕期每天晒太阳时间≥30 min是婴儿湿疹的保护因素（n P<0.05）。n 结论:孕期饮食结构、维生素D水平与婴儿湿疹发生有密切关系，故医务人员从孕早期就要对孕妇进行膳食营养、晒太阳时间及婴儿湿疹影响因素的相关指导，也有利于早期切断宫内传播，为减少婴儿湿疹的发生起到预防作用。“,”Objective:To investigate the relationship between dietary nutrition, 25-hydrodynamic Dn 3 (25-(OH) Dn 3) level in late pregnancy and infant eczema, and provided clinical evidence for the early prevention of infant eczema.n Methods:From January 2017 to December 2017, 365 pregnant women who underwent prenatal examination in the third trimester of pregnancy (28 to 40 weeks) in the outpatient department of obstetrics and gynecology of the people's hospital of Xinjiang autonomous region and delivered in hospital and their newborns were selected as subjects for prospective study. To enter the queue gestational age of 28 weeks or pregnant women must take a peripheral venous blood and detect the contents of pregnant women serum 25-(OH)Dn 3, at the same time for pregnant women vitamin D related factors during pregnancy and birth of the baseline survey, its after delivery was 6 months (1 month, 3 months, 6 months) of maternal and infant follow-up, observe the baby eczema, late pregnancy women was analyzed on the content of serum 25-(OH)D3 level and dietary nutrition during pregnancy in infant eczema.n Results:A total of 340 pairs with complete maternal and infant information were included in this study and were followed up for 6 months. Eczema occurred in 229 (62.74%) infants, of which 51.97% (119/229) occurred in 2-3 months after birth. Logistic regression results showed that frequent consumption of milk and eggs during pregnancy, consumption of spicy food, and maternal blood level of 25-(OH) Dn 3≤20 ng/ml in the third trimester of pregnancy were risk factors for infant eczema (n P<0.05), and daily exposure to sunlight≥30 min during pregnancy was a protective factor for infant eczema (n P<0.05).n Conclusion:Dietary structure and vitamin D level during pregnancy are related to the occurrence of infantile eczema. Therefore, medical personnel should provide guidance to pregnant women on dietary nutrition, sun exposure time and influencing factors of infantile eczema from early pregnancy, which is also conducive to cutting off intrauterine transmission at an early stage and plays an important role in reducing the occurrence of infantile eczema.