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目的:观察复方黄芪合剂对小鼠免疫功能的影响。方法:将实验小鼠随机分为复方黄芪合剂高剂量组(24 g·kg-1)、复方黄芪合剂低剂量组(12 g·kg-1)、香菇菌多糖片组(0.03 g·kg-1)和蒸馏水对照组,通过测定药物对小鼠的胸腺和脾脏指数、碳粒廓清吞噬指数(K)及校正吞噬指数(α)和血清溶血素抗体积数的影响,观察复方黄芪合剂对机体免疫功能的影响。结果:复方黄芪合剂可增强小鼠的脾脏指数(P<0.05)及胸腺指数(P<0.01),升高碳粒廓清吞噬指数(P<0.01)及校正吞噬指数(P<0.01),提高血清溶血素抗体积数(P<0.05,P<0.05)。结论:复方黄芪合剂对小鼠的特异性和非特异性免疫功能有促进作用。
Objective: To observe the effects of compound astragalus mixture on immune function in mice. Methods: The experimental mice were randomly divided into high-dose compound astragalus group (24 g · kg -1), low-dose compound astragalus group (12 g · kg -1), polysaccharides from Lentinus edodes (0.03 g · kg- 1) and distilled water control group, by measuring the effect of drug on thymus and spleen index, phagocytic index (K), corrected phagocytic index (α) and serum hemolysin antibody volume in mice, Impact of immune function. Results: The compound Astragalus mongholicus mixture could enhance the spleen index (P <0.05) and the thymus index (P <0.01), raise the phagocytic index (P <0.01) and correct phagocytic index (P <0.01) Hemolysin antibody volume (P <0.05, P <0.05). Conclusion: Compound Astragalus Mixture can promote specific and non-specific immune function in mice.