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目的 了解结核菌是否对冠状动脉造成损害。方法 以日本大耳白家兔为实验动物，Ｈ３７Ｒｖ 为实验菌株：一组家兔经钴＿６０ 辐射破坏免疫器官功能后静脉感染结核菌液（１０７／ｍｌ） ，一组家兔直接感染结核菌液。动物解剖后，脏器病理切片经Ｚ＿Ｎ 染色，ＨＥ 染色、三色（ＭＣＴ） 染色，ＢＣＧ 免疫组织化学染色和电镜观察。结果 结核菌随血行播散可到达心脏的任何部位并形成病变，冠状动脉的损害亦同样明显。免疫功能低下者将会导致结核的易感性和病变的严重性。结论 结核菌能导致冠状动脉的病理性损伤。
Objective To understand whether TB causes damage to the coronary arteries. Methods Japanese white rabbits were used as experimental animals and H37Rv was used as experimental strain. One group of rabbits received i.v. tuberculosis (107 / ml) intravenously after their immune function was damaged by cobalt-60 radiation. A group of rabbits was directly infected with tuberculosis bacilli . After the animal was dissected, the pathological sections of organs were stained with Z_N, HE, MCT, BCG immunohistochemistry and electron microscope. Results Mycobacterium tuberculosis disseminated with blood can reach any part of the heart and the formation of lesions, coronary lesions are also obvious damage. Immunocompromised people will lead to TB susceptibility and severity of the disease. Conclusion Mycobacterium tuberculosis can cause pathological damage of coronary artery.