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[目的]分析肺原发性黏液表皮样癌的临床病理特征,并探讨其诊断标准及预后。[方法]对31例肺原发黏液表皮样癌进行临床病理分析并复习相关文献。[结果]31例黏液表皮样癌患者中,低级别者13例,高级别者18例。患者多表现为咳嗽及痰中带血,偶有胸痛、胸闷和发热等症状。其中单纯肺楔形切除2例,单纯部分肺叶切除7例,部分肺叶切除+淋巴结清扫术14例,单侧全肺叶切除2例,6例无手术适应证。低级别和高级别患者手术后3年和5年生存率分别是100%、100%和63.6%、54.5%。[结论]肺原发性黏液表皮样癌是肺部少见的恶性肿瘤。组织形态学及生物学行为与涎腺的黏液表皮样癌相似。确诊主要靠组织病理学,并辅以免疫组化标记。此类型肿瘤生长缓慢,手术易切除,预后较好。
[Objective] To analyze the clinicopathological features of primary mucoepidermoid carcinoma of lung and to discuss its diagnostic criteria and prognosis. [Method] The clinical and pathological features of 31 cases of primary mucoepidermoid carcinoma of lung were reviewed and reviewed. [Results] Among the 31 cases of mucoepidermoid carcinoma, there were 13 cases of low grade and 18 cases of high grade. More patients with cough and bloody sputum, occasional chest pain, chest tightness and fever and other symptoms. Among them, simple pulmonary wedge resection in 2 cases, partial partial lobectomy in 7 cases, partial lobectomy + lymph node dissection in 14 cases, unilateral lobectomy in 2 cases, 6 cases without surgical indications. The 3-year and 5-year survival rates were 100%, 100% and 63.6%, 54.5% respectively in patients with low-grade and high-grade surgery. [Conclusion] Pulmonary primary mucoepidermoid carcinoma is a rare malignant tumor in lung. Histomorphology and biological behavior and salivary gland mucoepidermoid carcinoma similar. Confirmed mainly rely on histopathology, supplemented by immunohistochemical markers. This type of tumor growth is slow, surgical resection, the prognosis is good.