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目的了解云南省德宏州艾滋病病毒(HIV)感染者中乙型病毒性肝炎(乙肝)病毒(HBV)合并感染率,并分析其影响因素。方法对德宏州HIV感染者进行横断面调查,进行乙肝五项指标检测。结果在进行乙肝五项指标检测的5732例HIV感染者中,共有486例(8.5%)乙肝表面抗原(HBs Ag)阳性,2737例(47.7%)乙肝表面抗体(HBs Ab)阳性,102例(1.8%)乙肝e抗原(HBe Ag)阳性,522例(9.1%)乙肝e抗体(HBe Ab)阳性,3727例(65.0%)乙肝核心抗体(HBc Ab)阳性,90例(1.6%)感染者为乙肝“大三阳”(HBs Ag、HBe Ag和HBc Ab三项阳性)。多因素logistic回归分析显示,18~29岁年龄组“大三阳”阳性率高于50岁以上年龄组(OR=3.04,95%CI:1.30~7.15);男性“大三阳”阳性率高于女性(OR=1.77,95%CI:1.06~2.95)。结论德宏州HIV感染者中存在一定比例的HBV合并感染者;不同特征HIV感染者,HBV合并感染率不同。
Objective To understand the prevalence of hepatitis B virus (HBV) infection among HIV-infected people in Dehong Prefecture of Yunnan Province and to analyze its influencing factors. Methods A cross-sectional survey of HIV-infected persons in Dehong Prefecture was carried out, and five indicators of hepatitis B were detected. Results A total of 4832 (8.5%) HBs Ag positive were detected in 5,732 HIV-infected persons who tested for hepatitis B, 2737 (47.7%) were positive for HBs Ab, 102 1.8%) were positive for HBe Ag, 522 (9.1%) were positive for HBe Ab, 3727 (65.0%) were HBc Ab positive, and 90 (1.6% Hepatitis B “big three positive” (HBsAg, HBeAg and HBc Ab three positive). Multivariate logistic regression analysis showed that the positive rate of “Big Sanyang ” in 18-29 age group was higher than that in those over 50 (OR = 3.04, 95% CI: 1.30-7.15) The positive rate was higher in women than in women (OR = 1.77, 95% CI: 1.06-2.95). Conclusions There is a certain proportion of HBV co-infected persons among HIV-infected persons in Dehong Prefecture. HBV infection rates vary among HIV-infected persons with different characteristics.