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目的对2000～2007年上海市嘉定区男性居民前列腺癌发病死亡情况进行统计分析,了解其变化趋势并分析变化原因。方法根据上海市肿瘤登记处收集的2000～2007年上海市嘉定区前列腺癌的病例资料,并依据公安局提供的各年份不同年龄组平均人口数,计算发病率和死亡率,标化率的计算采用1976年世界标准人口。恶性肿瘤发病和死亡趋势分析采用肿瘤发病/死亡率时间趋势分析APC法。结果 2000～2007年间,上海市嘉定区肿瘤登记处共登记前列腺癌病例226例,前列腺癌的粗发病率呈明显的上升趋势,年均增长率为29.49%,死亡率增长相对缓慢,年均增长率为8.92%,2004～2007年发病率和死亡率较2000～2003年有较大幅度的上升。考虑人口构成后,标化发病率和死亡率时间趋势均不明显。年龄构成中,65岁及以上组发病和死亡的比重明显上升。结论前列腺癌发病和死亡绝对数上升趋势跟肿瘤登记报告的日益完善密切相关,同时人口老龄化、居民生活方式和其他环境暴露因素的改变也很大程度上影响了其趋势的变化。
Objective To analyze the incidence of prostate cancer death in male residents in Jiading District of Shanghai from 2000 to 2007, and to find out the trends and analyze the causes of the changes. Methods Based on the data of cases of prostate cancer collected from Shanghai Cancer Registry from 2000 to 2007 in Jiading District of Shanghai and calculate the incidence and mortality according to the average population of different age groups provided by the Public Security Bureau in each year, The 1976 world standard population. Cancer Incidence and Mortality Trend Analysis The cancer incidence / mortality trend analysis APC method was used. Results Between 2000 and 2007, a total of 226 cases of prostate cancer were registered in Jiading District Cancer Registry of Shanghai. The crude incidence rate of prostate cancer showed a significant upward trend with an average annual growth rate of 29.49%. The mortality rate was relatively slow and the average annual growth rate The rate was 8.22%. The incidence and mortality rate in 2004-2007 increased greatly from 2000 to 2003. After considering the population composition, the time trend of the standardized morbidity and mortality are not obvious. Age composition, the age group 65 and above the incidence and mortality increased significantly. Conclusions The absolute rising trend of the incidence and death of prostate cancer is closely related to the improvement of the tumor registration report. Meanwhile, the changes of population aging, residents’ life style and other environmental exposure factors also greatly affect the trend of the changes.