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早在中国古代,动物胆汁就已被作为一种镇咳药物使用,近一个世纪以来,医药科学领域有关于动物胆汁的研究越来越多,人们已经从原本对动物胆汁的镇咳效果研究逐渐深化到寻找动物胆汁中真正起到镇咳作用的有效物质。一系列国内外的研究者发现,胆汁酸是动物胆汁中含量最高的物质,而且动物胆汁的镇咳药效在很大程度上与胆汁酸有关。本文以前人的一些研究为基础,更进一步地去探讨胆汁酸的具体镇咳机制与药理作用。
As early as in ancient China, animal bile has been used as an antitussive drug. For nearly a century, there have been more and more studies on animal bile in the field of medical science. From the original research on the antitussive effect of animal bile, Deepen to look for animal bile really play a role in the antitussive effective substances. A series of researchers at home and abroad found that bile acids are the most abundant substances in animal bile, and the antitussive efficacy of animal bile is largely related to bile acids. Based on some previous studies, this article further explores the specific antitussive mechanism and pharmacological effects of bile acids.