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目的探讨原发性肾病综合征并发急性肾功能衰竭的临床治疗措施。方法回顾性分析45例患者的临床资料,对其临床疗效进行评价。结果 ARF临床治愈35例,好转7例,无效3例;PNS完全缓解36例,部分缓解6例,无效3例,总有效率95。ARF临床治愈35例,肾功能恢复正常所需时间为5～21d,好转7例,无效3例;PNS完全缓解36例,部分缓解6例,无效3例,总有效率95。结论急性肾功能衰竭合并原发性肾病综合征为可逆性改变,经及时治疗,一般预后较好。治疗的关键在于早期发现,早期纠正可逆因素。治疗应兼顾原发性肾病综合征和急性肾功能衰竭两个环节,促进ARF的恢复。
Objective To investigate the clinical treatment of primary nephrotic syndrome complicated with acute renal failure. Methods The clinical data of 45 patients were retrospectively analyzed and their clinical efficacy was evaluated. Results 35 cases of clinical cure ARF, improved in 7 cases, 3 cases were ineffective; PNS complete remission in 36 cases, partial remission in 6 cases, 3 cases, the total effective rate 95. ARF clinical cure in 35 cases, renal function returned to normal time required for 5 ~ 21d, improved in 7 cases, 3 cases of ineffective; PNS complete remission in 36 cases, 6 cases partially relieved, 3 cases ineffective, the total effective rate 95%. Conclusions Acute renal failure combined with primary nephrotic syndrome is a reversible change. After timely treatment, the prognosis is good. The key to treatment is early detection, early reversal of reversible factors. Treatment should take into account the two areas of primary nephrotic syndrome and acute renal failure, and promote the recovery of ARF.